PO-0735: Low dose Total Skin Irradiation followed by maintenance with oral Bexarotene in Mycosis Fungoides
نویسندگان
چکیده
منابع مشابه
[Autologous hematopoietic stem cell transplantation followed by oral bexarotene in a patient with advanced mycosis fungoides].
We describe the case of a 17-year-old patient with rapidly progressing and aggressive mycosis fungoides, with multiple cutaneous tumors and large cell transformation. She was initially treated with 3 cycles of high-dose chemotherapy with mega-CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) without response, leading to the decision to undertake autologous hematopoietic stem cel...
متن کاملRapidly progressive stage IVB mycosis fungoides treated with low-dose total skin electron beam therapy
Mycosis fungoides (MF) is the most common subtype of primary cutaneous T-cell lymphoma. Normally, MF has an indolent course although patients can progress to an advanced disease state (stages IIB-IVB). Advanced-stage disease is typically aggressive, leaving patients with debilitating symptoms and a decreased quality of life. Moreover, advanced-stage MF often proves refractory to therapy and car...
متن کاملDose Measurements in the Treatment of Mycosis Fungoides with Total Skin Irradiation using a 4 MeV Electron Beam
The total skin irradiation (TSI) is one of the most efficient techniques in the treatment administered with curative intent of the cutaneous T-cell lymphoma (mycosis fungoides). The cure may be obtained in 10% to 40% of the cases [13]. To irradiate all skin in an appropriate time of the machine, in most times, are used large electron fields with treatment distances about 3 meters. The original ...
متن کاملMycosis Fungoides of the Oral Cavity: Fungating Tumor Successfully Treated with Electron Beam Radiation and Maintenance Bexarotene
Oral involvement in mycosis fungoides is unusual and portends a poor prognosis. The clinical findings of three new cases are described along with a differential diagnosis and review of the literature. For brevity, only one patient is discussed in detail below whereas the other two cases are solely described in table form. The patient had a four-year history of mycosis fungoides before developin...
متن کاملThe utility of bexarotene in mycosis fungoides and Sézary syndrome
Cutaneous T-cell lymphoma (CTCL) is an umbrella term that encompasses a group of neoplasms that have atypical T-lymphocytes in the skin. Mycosis fungoides (MF) is the most common type of CTCL and Sézary syndrome (SS) is the leukemic form. Treatment for CTCL is dependent on the stage of disease and response to previous therapy. Therapy is divided into skin-directed treatment, which tends to be f...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2018
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(18)31045-4